Ng, who previously has interviewed for GM openings with the Dodgers and Mariners, was spotted having lunch with new Padres owner Jeff Moorad, and she was interviewed on Saturday.
Ng could be not reached by MLB.com for comment.
The Padres are looking for a replacement for Kevin Towers, who was dismissed after 14 seasons with the National League West franchise.
Ng was an assistant GM with the Yankees before going to the Dodgers, and prior to that, she worked as an executive with the White Sox. She has long been regarded as the leading candidate to become the Major Leagues' first female GM.
According to SI.com, Jed Hoyer, assistant GM of the Red Sox, is considered a favorite for the Padres job. Yankees executive Billy Eppler has been mentioned in the press as a candidate, but the Yankees said on Friday that the Padres had not requested permission to interview Eppler.
Moorad said in a phone interview a couple of weeks ago that he hoped to have a general manager in place within a few weeks and that he wouldn't be considering any in-house candidates or any candidates from the D-backs, his previous team.
Moorad told MLB.com on Oct. 6 that there was one minority candidate that the team would interview for the vacant GM job. Ng is Asian-American.
Jim Street is a reporter for MLB.com. This story was not subject to the approval of Major League Baseball or its clubs.