Wednesday's game is expected to mark the return to the mound of Zack Greinke, who left his first start after four pitches on Feb. 27 with a mild calf strain.
Mattingly is expected to return in time to manage Friday's game against the Cubs at new Cubs Park.
Ken Gurnick is a reporter for MLB.com. Cash Kruth is a reporter for MLB.com. Follow him on Twitter at @cashkruth. This story was not subject to the approval of Major League Baseball or its clubs.