"It's similar to the first time," said Crawford, who missed two games with a tight hamstring earlier this year. "It's just tight and sore, and I've been icing it.
Trainer Sue Falsone and manager Don Mattingly quickly made their way to second base and accompanied Crawford back to the dugout. He was replaced by Scott Van Slyke.
Crawford returned to the lineup Saturday after missing Friday night's game because he was still sore from running into the wall making a catch in Anaheim on Thursday night. He said he wasn't sure if the hamstring injury was related to the collision with the wall.
Manager Don Mattingly indicated the club needed to call up a healthy outfielder, and Yasiel Puig was held out of Double-A Chattanooga's lineup as a precaution in the event the club decides to bring him to Denver in time for Sunday's matinee.
Ken Gurnick is a reporter for MLB.com. This story was not subject to the approval of Major League Baseball or its clubs.