"It didn't really work today," said Ryu. "I'll continue practicing."
Ryu showed a sneaky fastball and a big-time changeup that caught Gordon Beckham looking for a called third strike.
"He looked pretty good, really," manager Don Mattingly said of Ryu.
Ryu pitched only one inning because the staff is easing him into a five-day routine coming from Korea, where he pitched every six days. He and Greinke will start split-squad games on Friday. Both threw an additional inning in the bullpen after they left the game.
Rookie catcher Tim Federowicz, who doubled and scored the Dodgers' first run, said both pitchers had solid fastball command. Federowicz said Greinke made life easy with a spot-on pregame scouting report on White Sox hitters.
"He knows what he's doing," Mattingly said, comparing Greinke to Clayton Kershaw in his spring approach.
Federowicz praised Ryu for his "laid-back" presence on the mound and quick adjustment following a high fastball.
Ryu said he got through the inning without a walk, "so I guess I succeeded. The ball felt extra slick for some reason. I need to get used to it."
The game was played on a cold and windy day, but Ryu appeared comfortable during and after the game, until he was asked about his weight, which is now listed at 255 pounds after 215 originally. He said he's lost 11 pounds since arriving in Arizona, but wouldn't confirm his current weight.
"Only I know how much I weigh," he said. "That's my No. 1 secret."
When told his weight was restated for the roster, he said: "If that's the case, I think a lot of players have to change, too."