Justin Sellers started in place of Dee Gordon at shortstop, while Juan Rivera was at first base in place of James Loney.
After Gordon went 0-for-4 with three fly-ball outs in Thursday's game against the Pirates, Mattingly felt Gordon looked a little fatigued and could use the day off.
"Dee hit some fly balls yesterday and kind of got out of his game. So, we'll give him a day off and get Justin out there," Mattingly said. "That is the beauty of having Justin. You get a guy who can really pick it at short. It is just the day for it."
With Gordon in his first full Major League season, Mattingly wants to make sure he's not overworked.
"He has a lot of responsibility, playing short and stealing bags," Mattingly said. "We are just giving him a mental day off, and it won't hurt him a bit."
While Loney did get his first hit of the season in Thursday's contest, he's struggled in his six starts this season, batting just .050 with two RBIs.
Mattingly said Loney will start the final two games against right-handers Joe Wieland and Edinson Volquez.
"I like playing our guys, and if James was crushing it, he would be in the lineup tonight, but he has struggled," Mattingly said. "It gets him a day.
"I just wanna get him going and let him line up and get him going against right-handers. We have two the next couple of days, and he'll be in there then."