And with a 1-2-3 ninth inning in the Dodgers' 3-2 win, Guerra notched save No. 5, which leads the Major Leagues.
"Sometimes they need a day off after one," Mattingly said before Thursday's game about Guerra and reliever Kenley Jansen. "Sometimes they throw a couple days in a row and feel all right."
Guerra saved each of the three games against the Pirates, and he's appeared in five of the Dodgers' seven games. Mattingly said he wouldn't necessarily be more cautious because the season just started.
"I play it safe all the time," he said. "I look at long range all the time. If we have a chance to get a save and Javy feels good, I'll use Javy. If Javy doesn't feel good and Kenley's good, I'll use Kenley."
Guerra has allowed one hit and struck out five in five scoreless innings.