Cedric Hunter hit a three-run homer and Anthony Rizzo had four hits, an RBI and two stolen bases to lead San Diego.
A pair of Casey Blake errors in the first inning -- one throwing and one fielding -- cost Dodgers starter Clayton Kershaw an unearned run, but he kept the damage to a minimum. Kershaw left after 4 1/3 innings having allowed four hits with two walks and three strikeouts.
A single by Rafael Furcal and a double by Juan Uribe off Wade LeBlanc tied the score in the bottom of the first.
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The Dodgers took a 2-1 lead in the second inning on a double by Marcus Thames, a single by Dioner Navarro and a sacrifice fly by Rod Barajas. LeBlanc finished with two runs allowed in four innings.
Jarrett Hoffpauir greeted Broxton with a tying home run leading off the sixth inning. Broxton, trying to rebound from a bad second half last year, didn't retire any of the five batters he faced, allowing three hits with a walk and a hit batter.
Kevin Frandsen's sacrifice fly off Minor League pitcher Stuart Pomeranz broke the tie and Hunter added a three-run homer for the Padres.
Padres up next: In what qualifies as a marquee matchup of sorts -- yes, we know it's Cactus League play and not a National League West tilt -- the Padres will send 14-game winner Mat Latos to the mound Friday against the Giants and pitcher Tim Lincecum at Peoria Stadium at 6:05 p.m. PT. Latos has struggled with command, walking six and allowing three runs while getting six outs across two starts. Other than better results, the Padres would like to see Latos reach four innings or 60 pitches in their first game against the Giants this spring.
Dodgers up next: The four regular infielders (James Loney, Uribe, Furcal and Blake) and left fielder Marcus Thames get the day off Friday as the Dodgers travel to Phoenix to play an Oakland A's split squad at 12:05 p.m. PT. Chad Billingsley gets the start for the Dodgers and is expected to be followed by Blake Hawksworth, Kenley Jansen and Javy Guerra. With none of the starting infield at the game, it will be another opportunity to look at the group fighting for a last position roster spot. It includes Xavier Paul, Russell Mitchell, Juan Castro, Aaron Miles and Justin Sellers.
Ken Gurnick is a reporter for MLB.com. This story was not subject to the approval of Major League Baseball or its clubs.